6-Bromoimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate
CAS: 372198-69-1
Molecular Formula: C10H9BrN2O2
6-Bromoimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester - Names and Identifiers
6-Bromoimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester - Physico-chemical Properties
| Molecular Formula | C10H9BrN2O2 |
| Molar Mass | 269.09 |
| Density | 1.60 |
| pKa | 2.29±0.50(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD10698068 |
6-Bromoimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester - Introduction
Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate is an organic compound with the chemical formula C10H8BrNO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or slightly light yellow crystal
-Melting point: 80-82°C
-Boiling point: 374.4°C
-Molecular weight: 249.08g/mol
Use:
- Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate are commonly used as intermediates in organic synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and pesticides.
Preparation Method:
The Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate is prepared as follows:
1. First prepare 6-bromoimidazo [1,2-A] pyridine-3-carboxylic acid:
-Reaction of pyridine and malonyldiazine in an anhydrous organic solvent to form its product.
-Bromination of the product to give 6-bromoimidazo [1,2-A] pyridine-3-carboxylic acid.
2. Preparation of Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate:
-6-Bromoimidazo [1,2-A] pyridine-3-carboxylic acid is reacted with acetic anhydride to produce an ethyl ester derivative.
Safety Information:
- Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate low toxicity, as a chemical substance, it should still be handled and stored safely.
-Avoid direct contact with skin and eyes, and ensure that good ventilation is provided during operation.
-Always wear appropriate protective equipment such as lab gloves and goggles when using the compound.
-If inhaled or ingested by mistake, seek medical attention immediately.
Nature:
-Appearance: colorless or slightly light yellow crystal
-Melting point: 80-82°C
-Boiling point: 374.4°C
-Molecular weight: 249.08g/mol
Use:
- Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate are commonly used as intermediates in organic synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and pesticides.
Preparation Method:
The Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate is prepared as follows:
1. First prepare 6-bromoimidazo [1,2-A] pyridine-3-carboxylic acid:
-Reaction of pyridine and malonyldiazine in an anhydrous organic solvent to form its product.
-Bromination of the product to give 6-bromoimidazo [1,2-A] pyridine-3-carboxylic acid.
2. Preparation of Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate:
-6-Bromoimidazo [1,2-A] pyridine-3-carboxylic acid is reacted with acetic anhydride to produce an ethyl ester derivative.
Safety Information:
- Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate low toxicity, as a chemical substance, it should still be handled and stored safely.
-Avoid direct contact with skin and eyes, and ensure that good ventilation is provided during operation.
-Always wear appropriate protective equipment such as lab gloves and goggles when using the compound.
-If inhaled or ingested by mistake, seek medical attention immediately.
Last Update：2024-04-09 20:15:17
![6-Bromoimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester](http://res.chembk.com/assets/str/2d/3/37/372198-69-1.png)